Invitrogen™ SELS Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA552686

Product Code. 15700641

Description

Immunogen sequence: EPDVVVKRQE ALAAARLKMQ EELNAQVEKH KEKLKQLEEE KRRQKIEMWD SMQEGKSYKG NAKKPQEEDS PGPSTSSVLK RKSDRKPLRG GGYNPLSGEG GGACSWRPGR Highest antigen sequence identity to the following orthologs: Mouse - 86%, Rat - 86%.

This gene encodes a transmembrane protein that is localized in the endoplasmic reticulum (ER). It is involved in the degradation process of misfolded proteins in the ER, and may also have a role in inflammation control. It participates in the transfer of misfolded proteins from the ER to the cytosol, where they are destroyed by the proteasome in a ubiquitin-dependent manner. This protein is a selenoprotein, containing the rare amino acid selenocysteine (Sec). Sec is encoded by the UGA codon, which normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, designated the Sec insertion sequence (SECIS) element, that is necessary for the recognition of UGA as a Sec codon, rather than as a stop signal.

Specifications

• Antigen: SELS
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SELENOS
• Gene Alias: 1500011E07Rik; AD-015; ADO15; C78786; chondroitin sulfate synthase 1; CHSY1; H4; H-4; H47; H-47; histocompatibility 47; MGC104346; MGC2553; minor histocompatibility antigen H47; SBBI8; selenoprotein S; Selenos; SELS; SEPS1; sg2; similar to selenoprotein S; Tanis; valosin-containing protein-interacting membrane protein; VCP interacting membrane selenoprotein; VCP-interacting membrane protein; VCP-interacting membrane selenoprotein; vimp; wu:fc16a03; zgc:136970
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 55829
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 0.2 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q9BQE4
• Gene Symbols: SELENOS
• Immunogen: Recombinant protein corresponding to Human SELS. Recombinant protein control fragment (Product #RP-90222).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG