Invitrogen™ SELS Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA543131

Product Code. 15585882

Description

Peptide sequence: PDVVVKRQEA LAAARLKMQE ELNAQVEKHK EKLKQLEEEK RRQKIEMWDS Sequence homology: Cow: 93%; Dog: 86%; Goat: 75%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 93%; Rabbit: 92%; Rat: 93%; Yeast: 90%; Zebrafish: 100%.

This gene encodes a transmembrane protein that is localized in the endoplasmic reticulum (ER). It is involved in the degradation process of misfolded proteins in the ER, and may also have a role in inflammation control. It participates in the transfer of misfolded proteins from the ER to the cytosol, where they are destroyed by the proteasome in a ubiquitin-dependent manner. This protein is a selenoprotein, containing the rare amino acid selenocysteine (Sec). Sec is encoded by the UGA codon, which normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, designated the Sec insertion sequence (SECIS) element, that is necessary for the recognition of UGA as a Sec codon, rather than as a stop signal.

Specifications

• Antigen: SELS
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SELENOS
• Gene Alias: 1500011E07Rik; AD-015; ADO15; C78786; chondroitin sulfate synthase 1; CHSY1; H4; H-4; H47; H-47; histocompatibility 47; MGC104346; MGC2553; minor histocompatibility antigen H47; SBBI8; selenoprotein S; Selenos; SELS; SEPS1; sg2; similar to selenoprotein S; Tanis; valosin-containing protein-interacting membrane protein; VCP interacting membrane selenoprotein; VCP-interacting membrane protein; VCP-interacting membrane selenoprotein; vimp; wu:fc16a03; zgc:136970
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 55829
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 2% sucrose and 0.09% sodium azide
• Gene Accession No.: Q9BQE4
• Gene Symbols: SELENOS
• Immunogen: Synthetic peptide directed towards the middle region of human SELS.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG