Invitrogen™ SCYL1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA529295

Product Code. 13443467

Description

Recommended positive controls: A431, H1299, HeLa. Predicted reactivity: Mouse (96%), Rat (94%), Xenopus laevis (83%), Bovine (97%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

With approximately 135 million base pairs and 1,400 genes, chromosome 11 makes up around 4% of human genomic DNA and is considered a gene and disease association dense chromosome. The chromosome 11 encoded Atm gene is important for regulation of cell cycle arrest and apoptosis following double strand DNA breaks. Atm mutation leads to the disorder known as ataxia-telangiectasia. The blood disorders Sickle cell anemia and β thalassemia are caused by HBB gene mutations. Wilms' tumors, WAGR syndrome and Denys-Drash syndrome are associated with mutations of the WT1 gene. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are also associated with defects in chromosome 11.

Specifications

• Antigen: SCYL1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Scyl1
• Gene Alias: 105 kDa kinase-like protein; 2810011O19Rik; C85140; Coated vesicle-associated kinase of 90 kDa; CVAK90; GKLP; HT019; likely ortholog of mouse N-terminal kinase-like protein; mdf; mfd; Mitosis-associated kinase-like protein NTKL; NKTL; N-terminal kinase-like protein; NTKL; P105; SCAR21; SCY1 like pseudokinase 1; SCY1-like 1 (S. cerevisiae); SCY1-like 1 splice variant 13; SCY1-like 1 splice variant 15; SCY1-like protein 1; SCY1-like, kinase-like 1; Scyl1; TAPK; TEIF; Telomerase regulation-associated protein; Telomerase transcriptional element-interacting factor; telomerase transcriptional elements-interacting factor; teratoma-associated tyrosine kinase; TRAP; ubiquitous protein kinase-like (105 kDa)
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 57410
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: Q96KG9
• Gene Symbols: Scyl1
• Immunogen: Recombinant protein encompassing a sequence within the center region of human SCYL1. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG