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Invitrogen™ SCN1B Polyclonal Antibody

Description
This antibody is predicted to react with bovine, rat and rabbit based on sequence homology.
Voltage-gated sodium channels are heteromeric proteins that function in the generation and propagation of action potentials in muscle and neuronal cells. They are composed of one alpha and two beta subunits, where the alpha subunit provides channel activity and the beta-1 subunit modulates the kinetics of channel inactivation. SCN1B encodes a sodium channel beta-1 subunit. Mutations in this gene result in generalized epilepsy with febrile seizures plus, Brugada syndrome 5, and defects in cardiac conduction. Multiple transcript variants encoding different isoforms have been found for this gene.
Specifications
Specifications
| Antigen | SCN1B |
| Applications | Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot |
| Classification | Polyclonal |
| Concentration | 0.48 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 0.09% sodium azide; pH 7.4 |
| Gene | Scn1b |
| Gene Accession No. | P97952, Q07699 |
| Gene Alias | ATFB13; BRGDA5; GEFSP1; Scn1b; sodium channel beta 1-subunit; sodium channel beta-1 subunit; sodium channel subunit beta-1; sodium channel voltage-gated type 1 beta polypeptide; sodium channel voltage-gated type I beta polypeptide; sodium channel, voltage gated, type I beta subunit; sodium channel, voltage-gated, type 1, beta polypeptide; sodium channel, voltage-gated, type I, beta; sodium channel, voltage-gated, type I, beta polypeptide; sodium channel, voltage-gated, type I, beta subunit; sodium voltage-gated channel beta subunit 1 |
| Gene Symbols | Scn1b |
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