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  6. Invitrogen™ SCIN Recombinant Rabbit Monoclonal Antibody (23GB4135), Invitrogen™

Invitrogen™ SCIN Recombinant Rabbit Monoclonal Antibody (23GB4135), Invitrogen™
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Product Code. 30088127
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30088127 100 μL 100µL
30087479 20 μL 20µL
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Product Code. 30088127 Supplier Invitrogen™ Supplier No. MA552658

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Description

Rabbit Recombinant Monoclonal Antibody

The SCIN gene, also known as scinderin, encodes for a calcium-dependent actin filament-severing protein that is involved in the regulation of the cytoskeleton. It plays a significant role in actin filament dynamics, influencing cellular processes such as cell shape, motility, secretion, and division. SCIN has been identified as a novel oncogene, with its abnormal expression strongly correlated to various cancers, including glioma and uterine corpus endometrial carcinoma. Specific mutations like S673F and S381Y in SCIN are linked with poor prognosis and are potential targets for cancer diagnosis, prognosis, and treatment strategies.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SCIN
Applications Flow Cytometry, Western Blot, Immunocytochemistry
Classification Recombinant Monoclonal
Clone 23GB4135
Concentration 0.45 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene SCIN
Gene Accession No. Q60604, Q9Y6U3
Gene Alias Adseverin; AW545522; Gelsolin-like protein; KIAA1905; SCIN; Scind; Scinderin
Gene Symbols SCIN
Host Species Rabbit
Immunogen A synthesized peptide derived from human SCIN (650-715AA).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 20259, 298975, 85477
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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