SCAMP2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Product Code	Brand	Quantity
16854154	Proteintech 15119-1-AP-20UL	20 μL
16844154	Proteintech 15119-1-AP-150UL	150 μL

Description

Secretory carrier membrane proteins (SCAMPs) are proteins that are components of post-Golgi membranes. These proteins are implicated to function in membrane trafficking. In fibroblasts, SCAMPs are concentrated in compartments that are involved in the recycling of cell surface receptors and endocytosis. In neurons, SCAMPs are associated with synaptic vesicles, secretion granules and transporter vesicles. SCAMPs are composed of four central transmembrane regions and a cytoplasmic tail. Of the five known SCAMPs, SCAMPs 1-3 contain cytoplasmic N-terminal regions with NPF repeats. NPF repeats are found to interact with EH domain proteins that function in budding of transport vesicles from the plasma membrane or the Golgi complex. SCAMPs 4 and 5 lack the N-terminal NPF repeats. SCAMPs 1-4 are all ubiquitously coexpressed while SCAMP 5 is only detectable in the brain. Studies show that SCAMP 5 is expressed late in development which is coincident with expansion of mature synapses.

Specifications

• Antigen: SCAMP2
• Applications: Immunoprecipitation, Immunofluorescence, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin)
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Mouse, Human, Rat
• Gene Accession No.: O15127, Q9ERN0
• Gene ID (Entrez): 10066, 24044, 65168
• Immunogen: SCAMP2 Fusion Protein Ag7190
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: SCAMP2

• Concentration: 0.25 mg/mL
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Alias: SCAMP2
• Gene Symbols: Scamp2
• Isotype: IgG
• Purification Method: Antigen Affinity Chromatography
• Product Type: Antibody