missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Chemicals
  4. Organic compounds
  5. Organoheterocyclic compounds
  6. Bi- and oligothiophenes
  7. SC 514, Tocris Bioscience™

SC 514, Tocris Bioscience™

Product Code. 18085512
Change view
Click to view available options
Quantity:
10 mg
50 mg
Unit Size:
10mg
50mg
2 product options available for selection
Product selection table with 2 available options. Use arrow keys to navigate and Enter or Space to select.
Product Code. Quantity unitSize
18085512 10 mg 10mg
18073982 50 mg 50mg
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 2 options available.
2 options
This item is not returnable. View return policy
Product Code. 18085512 Supplier Tocris Bioscience Supplier No. 3318/10

Please to purchase this item. Need a web account? Register with us today!

This item is currently unavailable or has been discontinued.
View the product page for possible alternatives.
 View alternative products

This item is not returnable. View return policy

Description

IKKβ inhibitor; attenuates NF-κB-induced gene expression

Orally active, ATP-competitive IKKβ inhibitor (IC50 = 3 - 12 μM) that displays > 10-fold selectivity over 28 other kinases including JNK, p38, MK2 and ERK. Attenuates NF-κB-induced gene expression of IL-6, IL-8 and COX-2 in synovial fibroblasts (IC50 values are 20, 20 and 8 μM respectively). Reduces iNOS induction and exhibits anti-inflammatory activity in vivo.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 354812-17-2
Molecular Formula C9H8N2OS2
Molecular Weight (g/mol) 224.296
InChI Key BMUACLADCKCNKZ-UHFFFAOYSA-N
Synonym 3-amino-5-thiophen-3-yl thiophene-2-carboxamide, 4-amino-2,3'-bithiophene-5-carboxamide, ikk-2 inhibitor, sc-514, insolution ikk-2 inhibitor, sc-514, 5-thien-3-yl-3-aminothiophene-2-carboxamide, curator_000007, 4-amino-2,3-bithiophene-5-carboxamide, biomolki_000076, biomolki2_000080, d0t6va
PubChem CID 2807869
IUPAC Name 3-amino-5-thiophen-3-ylthiophene-2-carboxamide
SMILES C1=CSC=C1C2=CC(=C(S2)C(=O)N)N

Specifications

Quantity 10 mg
Formula Weight 224.3
Percent Purity >98%
Chemical Name or Material SC 514
Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.