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STEMCELL Technologies SB202190

Artikelnummer. 17100102
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Quantity:
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25 mg
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10mg
25mg
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17100102 10 mg 10mg
17110102 25 mg 25mg
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Artikelnummer. 17100102 Leverandør STEMCELL Technologies Leverandørnr. 72632

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Beskrivelse

p38 MAPK inhibitor

  • SB202190 is a selective, potent, cell-permeable inhibitor of p38 MAP kinases, inhibiting p38α (SAPK2A, MAPK14) and p38β (SAPK2B, MAPK11) with IC50 values of 50 and 100 nM, respectively (Davies et al.; Jiang et al.) As a pyridinyl imidazole inhibitor, SB202190 directly binds p38 MAP kinases in the ATP binding pocket (Fox et al.)
  • Improves the self-renewal ability of neural stem cells from NPC1-deficient mice (Yang et al.)
  • Blocks adiponectin-mediated proliferation of hematopoietic stem cells (DiMascio et al.)
  • Reduces BMP3-mediated proliferation of C3H10T1/2 mesenchymal stem cells (Stewart et al.)
  • Induces cardiomyocyte differentiation from human embryonic stem cells (Graichen et al.)

Tekniske data

CAS 152121-30-7
Quantity 10 mg
Molecular Formula C20H14FN3O
Purity ≥98%
Produkttitel
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