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Tocris Bioscience™ SB 290157 trifluoroacetate
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Product Code. 18735426
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5 mg
Unit Size:
5mg
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18735426 5 mg 5mg
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Product Code. 18735426 Supplier Tocris Bioscience™ Supplier No. 6860/5
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Estimated Shipment: 31-07-2026
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Description

Potent C3a receptor antagonist

SB 290157 trifluoroacetate is a potent C3a receptor antagonist (IC50 values are 27 - 30 nM for C3a-induced Ca2+ mobilization in vitro and ex vivo). Inhibits C3a-induced chemotaxis in human mast cell line. Also inhibits tau hyperphosphorylation in vitro. Displays anti-inflammatory effects in animal models of airway inflammation and arthritis. Also inhibits glucose-induced insulin secretion and ATP production from ex vivo human and mouse pancreatic islets. Also exhibits C3a receptor agonist activity.
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Specifications

Chemical Name or Material N2-[2-(2,2-Diphenylethoxy)acetyl]-L-arginine trifluoroacetate
CAS 1140525-25-2
Quantity 5 mg
Molecular Formula C22H28N4O4.CF3CO2H
Purity 97%
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