SB 221284, Tocris Bioscience™

Description

Potent, selective 5-HT2C/2B receptor antagonist. pKi values are 6.4, 7.9 and 8.6 for 5-HT2A, 2B and 2C receptors respectively. Centrally active upon systemic administration in vivo.

Chemical Identifiers

• CAS: 196965-14-7
• Molecular Weight (g/mol): 353.363
• Synonym: tocris-1379, 2,3-dihydro-5-methylthio-n-3-pyridinyl-6-trifluoromethyl-1h-indole-1-carboxamide, 5-methylsulfanyl-n-pyridin-3-yl-6-trifluoromethyl-2,3-dihydroindole-1-carboxamide, d0dy5g, gtpl191, 5-methylthio-1-3-pyridylcarbamoyl-6-trifluoromethyl indoline, 5-methylthio-n-pyridin-3-yl-6-trifluoromethyl indoline-1-carboxamide, 5-methylsulfanyl-n-3-pyridyl-6-trifluoromethyl indoline-1-carboxamide
• ChEBI: CHEBI:8978
• SMILES: CSC1=C(C=C2C(=C1)CCN2C(=O)NC3=CN=CC=C3)C(F)(F)F

• Molecular Formula: C16H14F3N3OS
• InChI Key: OQZOXHCRSXYSPM-UHFFFAOYSA-N
• PubChem CID: 443389
• IUPAC Name: 5-methylsulfanyl-N-pyridin-3-yl-6-(trifluoromethyl)-2,3-dihydroindole-1-carboxamide

Specifications

• CAS: 196965-14-7
• Synonym: tocris-1379, 2,3-dihydro-5-methylthio-n-3-pyridinyl-6-trifluoromethyl-1h-indole-1-carboxamide, 5-methylsulfanyl-n-pyridin-3-yl-6-trifluoromethyl-2,3-dihydroindole-1-carboxamide, d0dy5g, gtpl191, 5-methylthio-1-3-pyridylcarbamoyl-6-trifluoromethyl indoline, 5-methylthio-n-pyridin-3-yl-6-trifluoromethyl indoline-1-carboxamide, 5-methylsulfanyl-n-3-pyridyl-6-trifluoromethyl indoline-1-carboxamide
• SMILES: CSC1=C(C=C2C(=C1)CCN2C(=O)NC3=CN=CC=C3)C(F)(F)F
• Molecular Weight (g/mol): 353.363
• ChEBI: CHEBI:8978
• Percent Purity: >99%

• Molecular Formula: C16H14F3N3OS
• InChI Key: OQZOXHCRSXYSPM-UHFFFAOYSA-N
• IUPAC Name: 5-methylsulfanyl-N-pyridin-3-yl-6-(trifluoromethyl)-2,3-dihydroindole-1-carboxamide
• PubChem CID: 443389
• Formula Weight: 353.36
• Chemical Name or Material: SB 221284

Safety and Handling

Recommended Storage : Store at +4°C