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SB 202190, MedChemExpress

Product Code. 16454826
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Product Code. 16454826 Supplier Medchem Express Supplier No. HY10295

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Description

MedChemExpress SB 202190 is a selective p38 MAP kinase inhibitor with IC50s of 50 nM and 100 nM for p38α and p38β2, respectively. SB 202190 binds to the ATP pocket of the active recombinant human p38 kinase with a Kd of 38 nM. SB 202190 has anti-cancer activity and rescued memory deficits. SB202190 induces autophagy.

SB 202190 is a selective p38 MAP kinase inhibitor with IC50s of 50 nM and 100 nM for p38α and p38β2, respectively. SB 202190 binds to the ATP pocket of the active recombinant human p38 kinase with a Kd of 38 nM. SB 202190 has anti-cancer activity and rescued memory deficits. SB202190 induces autophagy.

Specifications

Chemical Name or Material SB 202190
CAS 152121-30-7
Color Light Nude
Purity Grade Notes Research
Molecular Formula C20H14FN3O
Quantity 100 mg
Solubility Information DMSO : 100 mg/mL (301.80 mM; Need ultrasonic)
SMILES FC1=CC=C(C2=C(C3=CC=NC=C3)NC(C4=CC=C(O)C=C4)=N2)C=C1
Molecular Weight (g/mol) 331.34
Formula Weight 331.34
Percent Purity 98.56%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-Kinase/protease
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Research purposes only

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