SB 202190, MedChemExpress

Product Code. 16454826

Brand: Medchem Express HY10295

Description

MedChemExpress SB 202190 is a selective p38 MAP kinase inhibitor with IC50s of 50 nM and 100 nM for p38α and p38β2, respectively. SB 202190 binds to the ATP pocket of the active recombinant human p38 kinase with a Kd of 38 nM. SB 202190 has anti-cancer activity and rescued memory deficits. SB202190 induces autophagy.

SB 202190 is a selective p38 MAP kinase inhibitor with IC50s of 50 nM and 100 nM for p38α and p38β2, respectively. SB 202190 binds to the ATP pocket of the active recombinant human p38 kinase with a Kd of 38 nM. SB 202190 has anti-cancer activity and rescued memory deficits. SB202190 induces autophagy.

Specifications

• Chemical Name or Material: SB 202190
• CAS: 152121-30-7
• Color: Light Nude
• Purity Grade Notes: Research
• Molecular Formula: C₂₀H₁₄FN₃O
• Quantity: 100 mg
• Solubility Information: DMSO : 100 mg/mL (301.80 mM; Need ultrasonic)
• SMILES: FC1=CC=C(C2=C(C3=CC=NC=C3)NC(C4=CC=C(O)C=C4)=N2)C=C1
• Molecular Weight (g/mol): 331.34
• Formula Weight: 331.34
• Percent Purity: 98.56%
• Grade: Research
• Physical Form: Solid
• For Use With (Application): Cancer-Kinase/protease

Research purposes only