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Savolitinib, MedChemExpress

Product Code. 16492987
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Product Code. 16492987

Brand: Medchem Express HY15959

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Description

MedChemExpress Savolitinib (AZD-6094) is a potent, highly selective, and orally bioavailable c-Met inhibitor with IC50 s of 5 nM and 3 nM for c-Met and p-Met, respectively. Savolitinib (AZD-6094) selectively binds to and inhibits the activation of c-Met in an ATP-competitive manner, and disrupts c-Met signal transduction pathways. Antineoplastic activity.

Savolitinib (AZD-6094) is a potent, highly selective, and orally bioavailable c-Met inhibitor with IC50 s of 5 nM and 3 nM for c-Met and p-Met, respectively. Savolitinib (AZD-6094) selectively binds to and inhibits the activation of c-Met in an ATP-competitive manner, and disrupts c-Met signal transduction pathways. Antineoplastic activity.

Specifications

Chemical Name or Material Savolitinib
CAS 1313725-88-0
Color Off-White
Purity Grade Notes Research
Molecular Formula C17H15N9
Quantity 50 mg
Synonym Volitinib HMPL-504 AZD-6094
Solubility Information DMSO : 25 mg/mL (72.39 mM; Need ultrasonic)
SMILES CN1N=CC(C2=CN=C3C(N([C@H](C4=CN5C(C=C4)=NC=C5)C)N=N3)=N2)=C1
Molecular Weight (g/mol) 345.36
Formula Weight 345.36
Percent Purity 98.45%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-Kinase/protease
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Research purposes only

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