Invitrogen™ SART3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA528625

Product Code. 13402747

Description

Recommended positive controls: A431, H1299, HeLa, HepG2, Raji. Predicted reactivity: Rhesus Monkey (100%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

The protein encoded by this gene is an RNA-binding nuclear protein that is a tumor-rejection antigen. This antigen possesses tumor epitopes capable of inducing HLA-A24-restricted and tumor-specific cytotoxic T lymphocytes in cancer patients and may be useful for specific immunotherapy. This gene product is found to be an important cellular factor for HIV-1 gene expression and viral replication. It also associates transiently with U6 and U4/U6 snRNPs during the recycling phase of the spliceosome cycle. This encoded protein is thought to be involved in the regulation of mRNA splicing.

Specifications

• Antigen: SART3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SART3
• Gene Alias: AU045857; DSAP1; HIV-1 Tat-interacting protein of 110kDa; hSART-3; Kiaa0156; MGC138188; mKIAA0156; mSART-3; P100; p110; p110 nuclear RNA-binding protein; p110(nrb); RP11-13G14; Sart3; SART-3; spliceosome associated factor 3, U4/U6 recycling protein; squamous cell carcinoma antigen recognised by T cells 3; squamous cell carcinoma antigen recognized by T cells 3; squamous cell carcinoma antigen recognized by T-cells 3; Tat-interacting protein of 110 kDa; Tip110; Tumor-rejection antigen SART3
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 9733
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunocytochemistry
• Concentration: 0.52 mg/mL
• Formulation: 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: Q15020
• Gene Symbols: SART3
• Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human SART3. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG