Invitrogen™ SARS-CoV-2 Spike (N501Y Mutant) Recombinant Rabbit Monoclonal Antibody (HL1425)

Rabbit Recombinant Monoclonal Antibody

Brand:  Invitrogen™ MA547040

Product Code. 17849685

Description

Store as concentrated solution. Centrifuge briefly prior to opening vial.

The spike protein in SARS-CoV-2 (SARS-2-S) interacts with the human ACE2 receptor to gain entry into a cell to initiate infection SARS-2-S is cleaved into S1 and S2 subunits, with S1 serving the function of receptor-binding and S2 serving the function of membrane fusion The S protein undergoes two crucial cleavage events, with the first splitting S1 and S2 and the second splitting S2 into FP and S2' [PMID: 33466921].

Specifications

• Antigen: SARS-CoV-2 Spike (N501Y Mutant)
• Classification: Recombinant Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with no preservative
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Target Species: Virus
• Product Type: Antibody
• Isotype: IgG

• Applications: Western Blot
• Clone: HL1425
• Conjugate: Unconjugated
• Gene Alias: 2019-nCoV Spike; COVID-19 Spike; SARS-CoV-2 Spike
• Immunogen: Carrier-protein conjugated synthetic peptide surrounding mutant N501Y of SARS-CoV-2 (COVID-19) Spike. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid