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Invitrogen™ Sarcomeric alpha Actin Monoclonal Antibody (5C5)
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Product Code. 11591250
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Quantity:
6 mL
Unit Size:
6mL
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11591250 6 mL 6mL
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Product Code. 11591250 Supplier Invitrogen™ Supplier No. MA121597

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Description

Mouse Monoclonal Antibody

MA1-21597 detects alpha sarcomeric actin in bovine, guinea pig,human, rabbit, rat, fish, pig, snake, Xenopus and sheep samples.

The product encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Mutations in this gene cause nemaline myopathy type 3, congenital myopathy with excess of thin myofilaments, congenital myopathy with cores, and congenital myopathy with fiber-type disproportion, diseases that lead to muscle fiber defects.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Sarcomeric alpha Actin
Applications Immunohistochemistry (Paraffin)
Classification Monoclonal
Clone 5C5
Concentration Conc. Not Determined
Conjugate Unconjugated
Formulation Ascites with 0.09% sodium azide
Gene ACTA1
Gene Accession No. P68032, P68133, P68135
Gene Alias 0610041G09Rik; AA959943; AAT6; act; ACT-4; ACTA; acta1; ACTA1 protein; Acta2; Acta-2; ACTC; actc1; Actc-1; actc1.L; actg; actin; Actin alpha 1; actin alpha 1, skeletal muscle; actin alpha 2, smooth muscle; actin alpha cardiac; actin alpha cardiac 1; actin alpha cardiac muscle 1; actin, alpha 1, skeletal muscle; actin, alpha 2, smooth muscle, aorta; actin, alpha cardiac muscle 1; Actin, alpha cardiac muscle 1, intermediate form; Actin, alpha skeletal muscle; Actin, alpha skeletal muscle, intermediate form; actin, alpha, cardiac 1; actin, alpha, cardiac muscle; actin, alpha, cardiac muscle 1; actin, alpha, cardiac muscle 1 L homeolog; actin, alpha, vascular smooth muscle; actin, aortic smooth muscle; Actin, aortic smooth muscle, intermediate form; actna1; Acts; ACTSA; Actsk-1; ACTVS; alpha actin; alpha actin 1; alpha actin 2; alpha-actin cardiac; Alpha-actin-1; Alpha-actin-2; alphac-actin; alpha-cardiac actin; alphaSMA; alpha-sma; alpha-smooth muscle actin; ASD5; ASMA; a-SMA; B-actin; beta actin; beta-actin; cardiac actin; cardiac alpha actin; cardiac muscle alpha actin 1; cell growth-inhibiting gene 46 protein; CFTD; CFTD1; CFTDM; CMD1R; CMH11; cytoplasmic beta-actin; dfna20; dfna26; GIG46; hypothetical protein LOC515610; LOW QUALITY PROTEIN: actin, alpha skeletal muscle; LOW QUALITY PROTEIN: actin, aortic smooth muscle; LVNC4; MGC75587; MPFD; muscle actin; MYMY5; NEM1; NEM2; NEM3; nemaline myopathy type 3; SHPM; skeletal alpha actin; SMalphaA; smooth muscle alpha-actin; unnamed protein product; vascular smooth muscle alpha-actin; XELAEV_18039999mg
Gene Symbols ACTA1, ACTC1
Host Species Mouse
Immunogen Purified rabbit striated muscle actin.
Purification Method Purified
Quantity 6 mL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 100009506, 100340339, 58, 70
Target Species Human, Rabbit
Content And Storage 4°C
Product Type Antibody
Form Liquid
Isotype IgM
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