Invitrogen™ SAP18 Monoclonal Antibody (3B2)

Mouse Monoclonal Antibody

Brand:  Invitrogen™ MA524433

Product Code. 15612265

Description

Peptide Sequence: MAVESRVTQE EIKKEPEKPI DREKTCPLLL RVFTTNNGRH HRMDEFSRGN VPSSELQIYT WMDATLKELT SLVKEVYPEA RKKGTHFNFA IVFTDVKRPG YRVKEIGSTM SGRKGTDDSM TLQSQKFQIG DYLDIAITPP NRAPPTSGRM RPY.

SAP18 is involved in histone acetylation, which plays a key role in the regulation of eukaryotic gene expression. Histone acetylation and deacetylation are catalyzed by multisubunit complexes. The protein encoded by this gene is a component of the histone deacetylase complex, which includes SIN3, SAP30, HDAC1, HDAC2, RbAp46, RbAp48, and other polypeptides. This protein directly interacts with SIN3 and enhances SIN3-mediated transcriptional repression when tethered to the promoter. A pseudogene has been identified on chromosome 2.

Specifications

• Antigen: SAP18
• Classification: Monoclonal
• Conjugate: Unconjugated
• Gene: SAP18
• Gene Alias: 18 kDa Sin3-associated polypeptide; 2HOR0202; C530046K05Rik; cell growth inhibiting protein 38; cell growth-inhibiting gene 38 protein; cell growth-inhibiting protein 38; D11Ertd539e; EMegR4; GIG38; histone deacetlyase complex subunit SAP18; histone deacetylase complex subunit SAP18; SAP18; SAP18P; Sin3A associated protein 18; Sin3A associated protein 18kDa; Sin3A-associated protein, 18kDa; Sin3-associated polypeptide 18; sin3-associated polypeptide p18; sin3-associated polypeptide, 18 kDa; sin3-associated polypeptide, 18kDa; sin3-associated polypeptide, p18; Sinbp1
• Host Species: Mouse
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 10284
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot, Immunocytochemistry
• Clone: 3B2
• Formulation: PBS with no preservative; pH 7.4
• Gene Accession No.: O00422
• Gene Symbols: SAP18
• Immunogen: SAP18 (AAH30836, 1 a.a. ~ 153 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1 κ