Invitrogen™ SAFB Recombinant Rabbit Monoclonal Antibody (24GB4110)

Rabbit Recombinant Monoclonal Antibody

Product Code	Brand	Quantity
30275121	Invitrogen™ MA557245	100 μL
30275364	Invitrogen™ MA557246	20 μL

Description

SAFB Recombinant Monoclonal Antibody for Western Blot, ICC/IF, Flow

This gene encodes a DNA-binding protein which has high specificity for scaffold or matrix attachment region DNA elements (S/MAR DNA). This protein is thought to be involved in attaching the base of chromatin loops to the nuclear matrix but there is conflicting evidence as to whether this protein is a component of chromatin or a nuclear matrix protein. Scaffold attachment factors are a specific subset of nuclear matrix proteins (NMP) that specifically bind to S/MAR. The encoded protein is thought to serve as a molecular base to assemble a 'transcriptosome complex' in the vicinity of actively transcribed genes. It is involved in the regulation of heat shock protein 27 transcription, can act as an estrogen receptor co-repressor and is a candidate for breast tumorigenesis. This gene is arranged head-to-head with a similar gene whose product has the same functions. Multiple transcript variants encoding different isoforms have been found for this gene.

Specifications

• Antigen: SAFB
• Content And Storage: -20°C
• Classification: Recombinant Monoclonal
• Form: Liquid
• Isotype: IgG
• Target Species: Human, Mouse, Rat
• Gene: SAFB
• Gene Alias: 3110021E02Rik; 5330423C17Rik; AU018122; D18386; DKFZp779C1727; E130307D12; glutathione S-transferase fusion protein; HAP; heat-shock protein (HSP27) estrogen response element and TATA box-binding protein; HET; Hsp27 ERE-TATA binding protein; HSP27 ERE-TATA-binding protein; HSP27 estrogen response element-TATA box-binding protein; SAB-B1; Safb; SAF-B; Safb1; SAF-B1; scaffold attachment factor B; scaffold attachment factor B1
• Gene Symbols: SAFB
• Primary or Secondary: Primary
• Purification Method: Affinity chromatography

• Clone: 24GB4110
• Applications: Flow Cytometry, Western Blot, Immunocytochemistry
• Conjugate: Unconjugated
• Host Species: Rabbit
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: D3YXK2, O88453, Q15424
• Gene ID (Entrez): 224903, 6294, 64196
• Immunogen: A synthesized peptide derived from human SAFB (aa 881-915).
• Product Type: Antibody