Invitrogen™ SAA4 Recombinant Rabbit Monoclonal Antibody (JE47-81)

Rabbit Recombinant Monoclonal Antibody

Brand:  Invitrogen™ MA536134

Product Code. 17189335

Description

SAA4 Recombinant Monoclonal Antibody for Western Blot, IHC (P), Flow

Serum Amyloid A4 (SAA4) is a gene that encodes one of the constitutively expressed serum amyloid proteins. Located on chromosome 11, SAA4 is part of the serum amyloid A (SAA) superfamily, which includes other highly homologous genes like SAA1, SAA2, and SAA3. Unlike its counterparts, SAA4 is not an acute-phase reactant but is persistently expressed across different tissues, including plasma, where it associates with high-density lipoprotein (HDL). SAA4 is involved in lipid metabolism and inflammatory responses, albeit not directly induced by inflammatory stimuli like other SAA proteins. It appears as multiple isoforms, some of which may be glycosylated. Recent studies have shown that SAA4 expression encompasses a broad spectrum of physiological conditions and may serve as a marker in diseases involving chronic inflammation and persistent pathological states such as neovascular age-related macular degeneration. The gene's constitutive expression pattern suggests its fundamental role in maintaining homeostasis rather than responding dynamically to acute inflammatory challenges.

Specifications

• Antigen: SAA4
• Classification: Recombinant Monoclonal
• Concentration: 1 mg/mL
• Formulation: TBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
• Gene Accession No.: P35542
• Gene Symbols: Saa4
• Immunogen: Recombinant protein within Human SAA4 aa 1-130.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

• Applications: Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
• Clone: JE47-81
• Conjugate: Unconjugated
• Gene: Saa4
• Gene Alias: amyloid A-5 protein; Constitutively expressed serum amyloid A protein; CSAA; C-SAA; Saa4; Saa-4; Saa5; Saa-5; serum amyloid A 4; serum amyloid A-4 protein; serum amyloid A4, constitutive
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 6291
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid