Invitrogen™ S100B Monoclonal Antibody (CL2720)

Mouse Monoclonal Antibody

Brand:  Invitrogen™ MA534997

Product Code. 17155663

Description

Immunogen sequence: LEKAMVALID VFHQYSGREG DKHKLKKSEL KELINNELSH FLEEIKEQEV VDKVMETLDN DGDGECDFQE FMAFVAMVTT ACHEFFEHE Highest antigen sequence indentity to the following orthologs: Mouse - 99%, Rat - 98%.

S100B is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells and are involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100B may function in neurite extension, proliferation of melanoma cells, stimulation of Ca2+ fluxes, inhibition of PKC-mediated phosphorylation, astrocytosis and axonal proliferation, and inhibition of microtubule assembly. Chromosomal rearrangements and altered expression of this gene have been implicated in several diseases, including Alzheimer's disease, Down's syndrome, epilepsy, amyotrophic lateral sclerosis, melanoma, and type I diabetes.

Specifications

• Antigen: S100B
• Classification: Monoclonal
• Concentration: 1.0 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: P04271, P04631, P50114
• Gene Symbols: S100B
• Immunogen: Recombinant protein fragment of Human S100B (Product #RP-91304)
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG1

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Clone: CL2720
• Conjugate: Unconjugated
• Gene: S100B
• Gene Alias: AI850290; Bpb; hypothetical protein LOC525716; NEF; protein S100-B; S100; S100 calcium binding protein B; S100 calcium binding protein beta (neural); S100 calcium-binding protein B; S100 calcium-binding protein beta (neural); S-100 calcium-binding protein beta subunit; S100 calcium-binding protein, beta (neural); S-100 calcium-binding protein, beta chain; S100 protein beta chain; S-100 protein beta chain; S-100 protein subunit beta; S100 protein, beta polypeptide; S100 protein, beta polypeptide, neural; S100B; S100-B; S100beta; S100P
• Host Species: Mouse
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 20203, 25742, 6285
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid