Invitrogen™ RYK Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA130319

Product Code. 11517002

Description

Detects a band of approximately 67.5 kDa (predicted molecular weight: 72 kDa). Positive Control: Jurkat cell lysate. Store as concentrated solution. Centrifuge briefly prior to opening vial.

RYK is an atypical member of the family of growth factor receptor protein tyrosine kinases, differing from other members at a number of conserved residues in the activation and nucleotide binding domains. This gene product belongs to a subfamily whose members do not appear to be regulated by phosphorylation in the activation segment. It has been suggested that mediation of biological activity by recruitment of a signaling-competent auxiliary protein may occur through an as yet uncharacterized mechanism. A nine nucleotide insertion in some transcripts results in the SLG variant. It is not established whether this is a product of alternative splicing or a second gene, since evidence for a second gene or pseudogene on chromosome 17 exists.

Specifications

• Antigen: RYK
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: RYK
• Gene Alias: AW536699; D3S3195; ERK3; ERK-3; growth factor receptor; hydroxyaryl-protein kinase; JTK5; JTK5A; JTK5A protein tyrosine kinase; kinase VIK; Met-related kinase; Mrk; NYK-R; receptor-like tyrosine kinase; RYK; RYK1; tyrosine-protein kinase RYK; Vik
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 140585, 20187, 6259
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.40 mg/mL
• Formulation: PBS with 0.09% sodium azide
• Gene Accession No.: P34925, Q01887
• Gene Symbols: RYK
• Immunogen: KLH conjugated synthetic peptide between 160-190 amino acids from human RYK.
• Quantity: 400 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG