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Invitrogen™ RYK Monoclonal Antibody (F35 P7 D7 F5)
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Product Code. 11554393
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Quantity:
100 μg
Unit Size:
100µg
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11554393 100 μg 100µg
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Product Code. 11554393 Supplier Invitrogen™ Supplier No. MA1615

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Description

Mouse Monoclonal Antibody

This antibody detects RYK in human, mouse, and rat samples. MA1-615 has been successfully used in Western blot, procedures. By Western blot this antibody detects the RYK receptor-like tyrosine kinase-1 in cells. The MA1-615 immunogen corresponds to the ovalbumin-conjugated synthetic peptide C (462) L T E F H A A L G A Y V(475).

RYK is an atypical member of the family of growth factor receptor protein tyrosine kinases, differing from other members at a number of conserved residues in the activation and nucleotide binding domains. This gene product belongs to a subfamily whose members do not appear to be regulated by phosphorylation in the activation segment. It has been suggested that mediation of biological activity by recruitment of a signaling-competent auxiliary protein may occur through an as yet uncharacterized mechanism. A nine nucleotide insertion in some transcripts results in the SLG variant. It is not established whether this is a product of alternative splicing or a second gene, since evidence for a second gene or pseudogene on chromosome 17 exists.
TRUSTED_SUSTAINABILITY

Specifications

Antigen RYK
Applications Western Blot, Immunocytochemistry
Classification Monoclonal
Clone F35 P7 D7 F5
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 1mg/mL BSA and 0.05% sodium azide
Gene RYK
Gene Accession No. P34925, Q01887
Gene Alias AW536699; D3S3195; ERK3; ERK-3; growth factor receptor; hydroxyaryl-protein kinase; JTK5; JTK5A; JTK5A protein tyrosine kinase; kinase VIK; Met-related kinase; Mrk; NYK-R; receptor-like tyrosine kinase; RYK; RYK1; tyrosine-protein kinase RYK; Vik
Gene Symbols RYK
Host Species Mouse
Immunogen Synthetic peptide corresponding to residues C(462) L T E F H A A L G A Y V(475) of RYK, conjugated to ovalbumin.
Purification Method Protein G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 140585, 20187, 6259
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG1
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