missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Cell Culture Media, Supplements, and Reagents
  4. Cell Culture Reagents, Antibiotics and Supplements
  5. Antibiotics
  6. Ruxolitinib, MedChemExpress

Ruxolitinib, MedChemExpress

Product Code. 16431326
Encompass_Preferred
Click to view available options
Quantity:
5 mg
10 mg
50 mg
100 mg
200 mg
500 mg
1 g
Unit Size:
100mg
10mg
1g
200mg
500mg
50mg
5mg
This item is not returnable. View return policy

Product Code. 16431326

Brand: Medchem Express HY50856

Please to purchase this item. Need a web account? Register with us today!

This item is not returnable. View return policy

Description

MedChemExpress Ruxolitinib (INCB18424) is a potent and selective JAK1/2 inhibitor with IC50s of 3.3 nM and 2.8 nM in cell-free assays, and has 130-fold selectivity for JAK1/2 over JAK3. Ruxolitinib induces autophagy and kills tumor cells through toxic mitophagy.

Ruxolitinib (INCB18424) is a potent and selective JAK1/2 inhibitor with IC50s of 3.3 nM and 2.8 nM in cell-free assays, and has 130-fold selectivity for JAK1/2 over JAK3. Ruxolitinib induces autophagy and kills tumor cells through toxic mitophagy.

Specifications

Chemical Name or Material Ruxolitinib
Physical Form Powder
CAS 941678-49-5
Color White
Quantity 200 mg
Purity Grade Notes Research
Molecular Formula C17H18N6
For Use With (Application) Cancer-Kinase/protease
Synonym INCB18424
Solubility Information DMSO : ≥ 100 mg/mL (326.40 mM) ∣H2O : < 0.1 mg/mL (ultrasonic;warming;heat to 60°C) (insoluble)
SMILES N#CC[C@H](C1CCCC1)N2N=CC(C3=C4C=CNC4=NC=N3)=C2
Molecular Weight (g/mol) 306.37
Formula Weight 306.37
Percent Purity 95.37%
Grade Research
Show More Show Less

Research purposes only

Product Content Correction

The Fisher Scientific Encompass Program offers items which are not part of our distribution portfolio. These products typically do not have pictures or detailed descriptions. However, we are committed to improving your shopping experience. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Thank You! Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.