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Rucaparib, MedChemExpress

Product Code. 16494068
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Product Code. 16494068

Brand: Medchem Express HY10617A

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Description

MedChemExpress Rucaparib (AG014699) is an orally active, potent inhibitor of PARP proteins (PARP-1, PARP-2 and PARP-3) with a Ki of 1.4 nM for PARP1. Rucaparib is a modest hexose-6-phosphate dehydrogenase (H6PD) inhibitor. Rucaparib has the potential for castration-resistant prostate cancer (CRPC) research.

Rucaparib (AG014699) is an orally active, potent inhibitor of PARP proteins (PARP-1, PARP-2 and PARP-3) with a Ki of 1.4 nM for PARP1. Rucaparib is a modest hexose-6-phosphate dehydrogenase (H6PD) inhibitor. Rucaparib has the potential for castration-resistant prostate cancer (CRPC) research.

Specifications

Chemical Name or Material Rucaparib
CAS 283173-50-2
Color Green Yellow
Purity Grade Notes Research
Molecular Formula C19H18FN3O
Quantity 10 mg
Synonym AG014699 PF-01367338
Solubility Information DMSO : 25 mg/mL (77.31 mM; ultrasonic and adjust pH to 4 with HCl) ∣H2O : < 0.1 mg/mL (ultrasonic;warming;heat to 60°C) (insoluble)
SMILES FC1=CC2=C3C(CCNC2=O)=C(C4=CC=C(CNC)C=C4)NC3=C1
Molecular Weight (g/mol) 323.36
Formula Weight 323.36
Percent Purity 99.27%
Grade Research
Physical Form Powder
For Use With (Application) Cancer-programmed cell death
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Research purposes only

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