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Tocris Bioscience™ RU-SKI 43 hydrochloride

Hedgehog acyltransferase (Hhat) inhibitor; cell permeable


Description

Description

Hedgehog acyltransferase (Hhat) inhibitor (IC50 = 850 nM). Inhibits Sonic Hedgehog N (ShhN) palmitoylation in vitro. Has no effect on porcupine-induced fatty acid acylation of Wnt39a. Attenuates pancreatic cancer cell proliferation. Cell permeable.
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