RTCD1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 15996-1-AP-20UL

Product Code. 16875424

Description

RTCD1 catalyzes the conversion of 3′-phosphate to a 2′, 3′-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) the enzyme acts on RNA-N3′P to produce RNA-N3′PP5′A; (C) a non catalytic nucleophilic attack by the adjacent 2′hydroxyl on the phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing. There are two named isoforms.

Specifications

• Antigen: RTCD1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: RTCA
• Gene Alias: RNA 3 phosphate cyclase, RNA cyclase, RPC, RPC1, RTC1, RTCD1
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 295395, 66368, 8634
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.13 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: O00442, Q9D7H3
• Gene Symbols: RTCA, Rtcd1
• Immunogen: RTCD1 Fusion Protein Ag8904
• Quantity: 20 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG