Invitrogen™ RT1.D Monoclonal Antibody (OX-17), PE

Mouse Monoclonal Antibody

Brand:  Invitrogen™ MA517439

Product Code. 15378340

Description

MA5-17439 targets RT1.D in FACS applications and shows reactivity with Rat samples. The MA5-17439 immunogen is rat spleen membrane glycoproteins depleted of Ia-A antigens.

RT1.D is a gene located within the major histocompatibility complex (MHC) region of the rat genome, specifically part of the RT1 complex. RT1.D, along with its counterpart RT1.B, comprises class II MHC genes, which are key players in the adaptive immune response. These genes encode for proteins that present extracellularly derived peptides to helper T cells (CD4+ T cells), facilitating the activation and regulation of immune responses. The RT1.D gene product is analogous to human HLA-DR and mouse I-A/I-E molecules, playing an essential role in antigen presentation and immune recognition. RT1.D genes are highly polymorphic, which influences susceptibility to various diseases and are often utilized in studies involving autoimmune diseases, immune response, and transplantation immunology.

Specifications

• Antigen: RT1.D
• Classification: Monoclonal
• Concentration: 0.1 mg/mL
• Formulation: PBS with 4-5mg/mL BSA and 0.02% sodium azide
• Gene Accession No.: P18211
• Gene Symbols: RT1-Db1
• Immunogen: Rat spleen membrane glycoproteins depleted of Ia-A antigens.
• Quantity: 50 μg
• Primary or Secondary: Primary
• Target Species: Rat
• Product Type: Antibody
• Isotype: IgG1

• Applications: Flow Cytometry
• Clone: OX-17
• Conjugate: PE
• Gene: RT1-Db1
• Gene Alias: Db1; MHC class II RT1D beta1 chain antigen; rano class II histocompatibility antigen, D-1 beta chain; rat class I D; RT1 class II histocompatibility antigen, D-1 beta chain; RT1 class II, locus Db1; RT1-D beta; RT1-Db; RT1-Db1; RT1-Db1n
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 294270
• Content And Storage: 4°C, do not freeze
• Form: Liquid