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Invitrogen™ RSK2 Monoclonal Antibody (4E10)
Description
MA5-15920 targets RSK2 in indirect ELISA, FACS, IF, and WB applications and shows reactivity with Human samples. The MA5-15920 immunogen is purified recombinant fragment of human RSK2 expressed in E. Coli. . MA5-15920 detects RSK2 which has a predicted molecular weight of approximately 80kDa.
RPS6KA3 (RSK2) is a serine/threonine kinase that modulates many cellular processes including transcription, adhesion, growth, survival, and proliferation. RPS6KA3 contains 2 non-identical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Mutations in the gene have been associated with Coffin-Lowry syndrome (CLS).
Specifications
Specifications
| Antigen | RSK2 |
| Applications | ELISA, Flow Cytometry, Western Blot, Immunocytochemistry |
| Classification | Monoclonal |
| Clone | 4E10 |
| Concentration | Conc. Not Determined |
| Conjugate | Unconjugated |
| Formulation | ascites with 0.03% sodium azide |
| Gene | RPS6KA3 |
| Gene Accession No. | P51812 |
| Gene Alias | 90 kDa ribosomal protein S6 kinase 3; C130006E23; CLS; HU-3; Insulin-stimulated protein kinase 1; ISPK1; ISPK-1; MAP kinase-activated protein kinase 1b; MAPK-activated protein kinase 1b; MAPKAP kinase 1b; MAPKAPK1B; MAPKAPK-1b; MPK-9; MRX19; p90-RSK 3; p90-RSK2; p90RSK3; pp90RSK2; RGD1563860; ribosomal protein S6 kinase 2; ribosomal protein S6 kinase A3; ribosomal protein S6 kinase alpha-3; ribosomal protein S6 kinase polypeptide 3; ribosomal protein S6 kinase, 90kDa, polypeptide 3; ribosomal S6 kinase 2; Rps6ka3; Rps6ka-rs1; RSK; Rsk2; RSK-2; S6K-alpha3; S6K-alpha-3 |
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