Invitrogen™ RRAGC Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA584256

Product Code. 16391205

Description

Immunogen sequence: MSLQYGAEET PLAGSYGAAD SFPKDFGYGV EEEEEE Highest antigen sequence indentity to the following orthologs: Rat - 100%, Mouse - 100%.

RRAGC (Ras-related GTP-binding protein C) is a monomeric guanine nucleotide-binding protein that plays a crucial role in the cellular response to amino acid availability through regulations of the mTORC1 signaling cascade. RRAGC forms a heterodimer with RRAGA and RRAGB and is primarily localized to the cytoplasm. It cycles between an inactive GTP-bound and an active GDP-bound form. RRAGC, in its active form, participates in the re-localization of mTORC1 to the lysosomes and its subsequent activation by the GTPase RHEB. This re-localization is a crucial step in the activation of the TOR signaling cascade by amino acids.

Specifications

• Antigen: RRAGC
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Rragc
• Gene Alias: AU041672; GTPase-interacting protein 2; GTR2; Rag C; Rag C protein; RAGC; Ras related GTP binding C; Ras-related GTP binding C; ras-related GTP-binding protein C; RRAGC; small GTPase homolog; small GTPase, homolog; TIB929; YGR163W
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 64121
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunocytochemistry, Immunofluorescence
• Concentration: 0.3 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q9HB90
• Gene Symbols: Rragc
• Immunogen: Recombinant protein corresponding to Human RRAGC. Recombinant protein control fragment (Product #RP-106640).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG