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Invitrogen™ RRAD Polyclonal Antibody
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Product Code. 15554821
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Quantity:
100 μg
Unit Size:
100µg
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15554821 100 μg 100µg
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Product Code. 15554821 Supplier Invitrogen™ Supplier No. PA537885

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Description

Goat Polyclonal Antibody

This antibody is predicted to react with human, rat, dog, pig and cow based on sequence homology. This antibody is tested in Peptide ELISA: antibody detection limit dilution 64,000.

The Ras-encoded family of proteins bind GDP and GTP with high affinity. They possess a low level of intrinsic GTPase activity that increases more than 100-fold when interacting with cytosolic GTPase activating protein (GAP). Ras family members include H-Ras, K-Ras, N-Ras, M-Ras, R-Ras, ERas, Rheb, TC 21, RASL11B and Rad (Ras associated with diabetes) GTPase.Rad GTPase is a GTP-binding protein that is similar to Ras but has unique features. Unlike other small GTPases, Rad GTPase lacks typical pren-ylation motifs at its C terminus. The Rad GTPase enzyme binds calmodulin, inhibits vascular lesion formation, has low intrinsic GTPase activity and cannot be stimulated by any known GAP molecules. Rad GTPase is expressed in skeletal muscle, cardiac muscle and lung tissues and is overexpressed in the skeletal muscle tissue of individuals with type II diabetes.
TRUSTED_SUSTAINABILITY

Specifications

Antigen RRAD
Applications Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Gene RRAD
Gene Accession No. O88667
Gene Alias GTP-binding protein RAD; RAD; RAD1; RAS (RAD and GEM) like GTP binding 3; ras associated with diabetes; Ras-like GTP-binding protein rad; Ras-related associated with diabetes; REM3; RRAD; RRAD, Ras related glycolysis inhibitor and calcium channel regulator; RRAD, Ras related glycolysis inihibitor and calcium channel regulator
Gene Symbols RRAD
Host Species Goat
Immunogen Peptide with sequence C-HRRSMPVDERDLQ, from the internal region of RRAD (aa36-48).
Purification Method Ammonium sulfate precipitation
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 56437
Target Species Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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