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  5. Tocris Bioscience™ RQ 00203078

Tocris Bioscience™ RQ 00203078
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Product Code. p-5545595
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Quantity:
10 mg
50 mg
Unit Size:
10mg
50mg
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Product Code. 18778218

Brand: Tocris Bioscience™ 5388/10

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Description

Potent and selective TRPM8 antagonist; orally active

RQ 00203078 is a potent TRPM8 antagonist (IC50 values are 5.3 and 8.3 nM for rat and human channels respectively). Exhibits >350-fold selectivity for TRPM8 over TRPV4, TRPV1 and TRPA1. Reduces HSC3 and HSC4 oral squamous carcinoma cell migration and invasion in vitro. Also attenuates icilin -induced wet dog shakes in rats. Orally active.
TRUSTED_SUSTAINABILITY

Specifications

Quantity 10 mg
Product Type RQ 00203078
Purity >98%
Molecular Weight (g/mol) 554.85

For Research Use Only

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