Invitrogen™ RPL36 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA575385

Product Code. 15911915

Description

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

The exosome is involved in a multitude of cellular RNA processing and degradation events. DIS3, also known as exosome complex exonuclease RRP44, is a ribonuclease that acts directly in the processing, turnover, and surveillance of a large number of distinct RNA species. DIS3 localizes to both the cytoplasm and the nucleus and contains one PINc domain. It is widely expressed with highest expression in testis and is required for processing of 7S pre-RNA into a mature nuclear complex and, ultimately, for proper mitotic progression. Abnormal expression levels of DIS3 may be associated with colon cancer, suggesting a role for DIS3 in tumorigenesis.

Specifications

• Antigen: RPL36
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Rpl36
• Gene Alias: 60S ribosomal protein L36; L36; Large ribosomal subunit protein eL36; ribosomal protein L36; RPL36
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 25873, 54217, 58927
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: P39032, P47964, Q9Y3U8
• Gene Symbols: Rpl36
• Immunogen: Synthetic peptide corresponding to amino acids 60-105 of Human RPL36.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG