Invitrogen™ RPL23 Polyclonal Antibody

Goat Polyclonal Antibody

Brand:  Invitrogen™ PA537913

Product Code. 15524851

Description

This antibody is predicted to react with rat, pig and cow based on sequence homology. This antibody is tested in Peptide ELISA: antibody detection limit dilution 128,000.

This gene encodes a ubiquitously expressed nuclear protein which belongs to a highly conserved subfamily of WD-repeat proteins. It is present in protein complexes involved in histone acetylation and chromatin assembly. It is part of the Mi-2 complex which has been implicated in chromatin remodeling and transcriptional repression associated with histone deacetylation. This encoded protein is also part of co-repressor complexes, which is an integral component of transcriptional silencing. It is found among several cellular proteins that bind directly to retinoblastoma protein to regulate cell proliferation. This protein also seems to be involved in transcriptional repression of E2F-responsive genes. Three transcript variants encoding different isoforms have been found for this gene.

Specifications

• Antigen: RPL23
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: RPL23
• Gene Alias: 2810009A01Rik; 60S ribosomal protein L17; 60S ribosomal protein L23; L23; Large ribosomal subunit protein uL14; MGC111167; MGC117346; MGC72008; ribosomal protein L17; ribosomal protein L23; rpL17; Rpl23
• Host Species: Goat
• Purification Method: Ammonium sulfate precipitation
• Regulatory Status: RUO
• Gene ID (Entrez): 65019, 9349
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.5 mg/mL
• Formulation: TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P62829, P62830
• Gene Symbols: RPL23
• Immunogen: Peptide with sequence KECADLWPRIASN, from the C-terminus of RPL23 (aa 123-135).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG