RPL22 Rabbit anti-Human, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Product Code	Brand	Quantity
16863525	Proteintech 25002-1-AP-20UL	20 μL
16853525	Proteintech 25002-1-AP-150UL	150 μL

Description

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a cytoplasmic ribosomal protein that is a component of the 60S subunit. The protein belongs to the L22E family of ribosomal proteins. Its initiating methionine residue is post-translationally removed. The protein can bind specifically to Epstein-Barr virus-encoded RNAs (EBERs) 1 and 2. The mouse protein has been shown to be capable of binding to heparin. Transcript variants utilizing alternative polyA signals exist. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. It was previously thought that this gene mapped to 3q26 and that it was fused to the acute myeloid leukemia 1 (AML1) gene located at 21q22 in some therapy-related myelodysplastic syndrome patients with 3;21 translocations; however, these fusions actually involve a ribosomal protein L22 pseudogene located at 3q26, and this gene actually maps to 1p36.3-p36.2.

Specifications

• Antigen: RPL22
• Applications: Immunocytochemistry, Western Blot, Immunofluorescence
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Human
• Gene Accession No.: P35268
• Gene ID (Entrez): 6146
• Immunogen: RPL22 Fusion Protein Ag21851
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: RPL22

• Concentration: 0.33 mg/mL
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
• Gene Alias: 60S ribosomal protein L22, EAP, EBER associated protein, HBP15, HBP15/L22, Heparin binding protein HBp15, ribosomal protein L22, RPL22
• Gene Symbols: RPL22
• Isotype: IgG
• Purification Method: Antigen Affinity Chromatography
• Product Type: Antibody