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Invitrogen™ RPAIN Polyclonal Antibody
Description
A suggested positive control is Jurkat cell lysate. PA5-20327 can be used with blocking peptide PEP-0447.
Replication protein A (RPA) is a single-stranded-DNA binding protein involved in numerous eukaryotic DNA processes including replication, repair and recombination. RPA interacting protein (RPA IP) has been identified as an adapter protein that is involved in RPA nuclear import instead of the prototypical importin proteins that normally mediate nuclear import. Multiple isoforms of RPA IP are known to exist, with the longest isoform localized to the cytoplasm. Isoform 2 is sumoylated and is located in the PML nuclear body within the nucleus. It has been suggested that this isoform mediates the localization of the RPA complex into the PML nuclear body, thereby participating in RPA function in DNA metabolism.
Specifications
Specifications
| Antigen | RPAIN |
| Applications | Western Blot |
| Classification | Polyclonal |
| Concentration | 1 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 0.02% sodium azide |
| Gene | RPAIN |
| Gene Accession No. | Q4G2Y1, Q86UA6, Q9CWY9 |
| Gene Alias | 2400006N03Rik; hRIP; nuclear transporter; RAP interaction protein; RAP interaction protein alpha; RGD1308492; RIP; RPA interacting protein; RPA interacting protein delta 2; RPA interacting protein epsilon; RPAIN; RPA-interacting protein |
| Gene Symbols | RPAIN |
| Show More |
Product Title
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