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Rotenone, Tocris Bioscience™
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Inhibits complex I of the mitochondrial electron transport chain

Brand:  Tocris Bioscience 3616/50

Quantity 50 mg

Product Code. 18792594

  • £82.00 / 50mg

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Description

Description

Mitochondrial electron transport chain inhibitor (IC50 = 1.7 - 2.2 μM at complex I). Inhibits NADH oxidation by cardiac sarcoplasmic reticulum (IC50 = 3.4 nM). Commonly used pesticide and induces Parkinsonism in animal models. May also inhibit autophagy induction; blocks lysosomal degradation of autophagic vacuoles. Cell-permeable and brain penetrant.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

83-79-4
50 mg
JUVIOZPCNVVQFO-HBGVWJBISA-N
394.423
CHEBI:28201
>95%
C23H22O6
rotenone, dactinol, paraderil, --rotenone, tubatoxin, barbasco, --cis-rotenone, derrin, derris, cube root
CC(=C)C1CC2=C(O1)C=CC3=C2OC4COC5=CC(=C(C=C5C4C3=O)OC)OC
6758
394.42
Rotenone
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