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Rosuvastatin Calcium, MedChemExpress

Product Code. 16453397
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Product Code. 16453397

Brand: Medchem Express HY17504

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Description

MedChemExpress Rosuvastatin Calcium is a competitive HMG-CoA reductase (HMGCR) inhibitor, with an IC50 of 11 nM.

Rosuvastatin Calcium potently blocks hERG current with an IC50 of 195 nM. Rosuvastatin Calcium reduces the expression of the mature hERG and the interaction of heat shock protein 70 (Hsp70) with the hERG protein. Rosuvastatin Calcium effectively lowers low-density lipoprotein (LDL) cholesterol, triglycerides, and C-reactive protein levels.

Specifications

Chemical Name or Material Rosuvastatin Calcium
CAS 147098-20-2
Color White
Purity Grade Notes Research
Molecular Formula C22H27Ca0.5FN3O6S
Quantity 50 mg
Synonym Rosuvastatin hemicalcium ZD 4522 Calcium
Solubility Information DMSO : 25 mg/mL (49.94 mM; Need ultrasonic) ∣H2O : 1 mg/mL (2.00 mM; Need ultrasonic)
SMILES O=C([O-])C[C@H](O)C[C@H](O)/C=C/C1=C(C(C)C)N=C(N(C)S(=O)(C)=O)N=C1C2=CC=C(F)C=C2.[0.5Ca2+]
Molecular Weight (g/mol) 500.57
Formula Weight 500.57
Percent Purity 96.75%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-programmed cell death
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Research purposes only

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