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Romidepsin, MedChemExpress

Product Code. 16428917
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Product Code. 16428917

Brand: Medchem Express HY15149

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Description

MedChemExpress Romidepsin (FK 228) is a Histone deacetylase (HDAC) inhibitor with anti-tumor activities. Romidepsin (FK 228) inhibits HDAC1, HDAC2, HDAC4, and HDAC6 with IC50s of 36 nM, 47 nM, 510 nM and 1.4 μM, respectively. Romidepsin (FK 228) is produced by Chromobacterium violaceum, induces cell G2/M phase arrest and apoptosis.

Romidepsin (FK 228) is a Histone deacetylase (HDAC) inhibitor with anti-tumor activities. Romidepsin (FK 228) inhibits HDAC1, HDAC2, HDAC4, and HDAC6 with IC50s of 36 nM, 47 nM, 510 nM and 1.4 μM, respectively. Romidepsin (FK 228) is produced by Chromobacterium violaceum, induces cell G2/M phase arrest and apoptosis.

Specifications

Chemical Name or Material Romidepsin
Physical Form Solid
CAS 128517-07-7
Color White
Quantity 5 mg
Purity Grade Notes Research
Molecular Formula C24H36N4O6S2
For Use With (Application) Cancer-programmed cell death
Synonym FK 228 FR 901228 NSC 630176
Solubility Information DMSO : ≥ 100 mg/mL (184.95 mM)
SMILES C/C=C(NC([C@@H](CSSCC/C=C/[C@@H](O1)CC2=O)NC([C@@H](C(C)C)N2)=O)=O)/C(N[C@@H](C(C)C)C1=O)=O
Molecular Weight (g/mol) 540.7
Formula Weight 540.7
Percent Purity 96.89%
Grade Research
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Research purposes only

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