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Rofecoxib, MedChemExpress

Product Code. 16427266
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100 mg
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Product Code. 16427266 Supplier Medchem Express Supplier No. HY17372

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Description

MedChemExpress Rofecoxib is a potent, specific and orally active COX-2 inhibitor, with IC50s of 26 and 18 nM for human COX-2 in human osteosarcoma cells and Chinese hamster ovary cells, with a 1000-fold selectivity for COX-2 over human COX-1 (IC50 > 50 μM in U937 cells and > 15 μM in Chinese hamster ovary cells).

Rofecoxib is a potent, specific and orally active COX-2 inhibitor, with IC50s of 26 and 18 nM for human COX-2 in human osteosarcoma cells and Chinese hamster ovary cells, with a 1000-fold selectivity for COX-2 over human COX-1 (IC50 > 50 μM in U937 cells and > 15 μM in Chinese hamster ovary cells).

Specifications

Chemical Name or Material Rofecoxib
CAS 162011-90-7
Color Light Yellow
Purity Grade Notes Research
Molecular Formula C17H14O4S
Quantity 100 mg
Synonym MK 966
Solubility Information DMSO : 33.33 mg/mL (106.02 mM; Need ultrasonic)
SMILES O=C1OCC(C2=CC=C(S(=O)(C)=O)C=C2)=C1C3=CC=CC=C3
Molecular Weight (g/mol) 314.36
Formula Weight 314.36
Percent Purity 99.75%
Grade Research
Physical Form Solid
For Use With (Application) COVID-19-immunoregulation
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Research purposes only

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