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Ro3280, MedChemExpress

Product Code. 16492447
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Product Code. 16492447 Supplier Medchem Express Supplier No. HY15161

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MedChemExpress Ro3280 is a potent, highly selective inhibitor of PLK1 with an IC50 and a Kd of 3 nM and 0.09 nM, respectively, and nearly has no effect on PLK2 and PLK3.

Ro3280 is a potent, highly selective inhibitor of PLK1 with an IC50 and a Kd of 3 nM and 0.09 nM, respectively, and nearly has no effect on PLK2 and PLK3.

Specifications

Chemical Name or Material Ro3280
CAS 1062243-51-9
Color White
Purity Grade Notes Research
Molecular Formula C27H35F2N7O3
Quantity 50 mg
Solubility Information DMSO : 100 mg/mL (183.96 mM; Need ultrasonic)
SMILES COC1=C(NC2=NC(N(C3CCCC3)CC(F)(F)C(N4C)=O)=C4C=N2)C=CC(C(NC5CCN(C)CC5)=O)=C1
Molecular Weight (g/mol) 543.61
Formula Weight 543.61
Percent Purity 98.09%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-Kinase/protease
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Research purposes only

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