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Ro 51, Tocris Bioscience™
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Product Code. 18035862
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Product Code. 18035862 Supplier Tocris Bioscience Supplier No. 4391/10

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Description

Potent P2X3, P2X2/3 antagonist

Potent, dual P2X3 and P2X2/3 antagonist (IC50 values are 2 and 5 nM for rP2X3 and hP2X2/3 respectively). Selective for P2X3 and P2X2/3 over other P2X receptors (IC50 values are > 10 μM for P2X1, P2X2, P2X4, P2X5, and P2X7). Cell permeable.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 1050670-85-3
Molecular Formula C17H23IN4O4
Molecular Weight (g/mol) 474.299
InChI Key PAYROHWFGZADBR-UHFFFAOYSA-N
Synonym 2-4-amino-5-5-iodo-2-isopropyl-4-methoxyphenoxy pyrimidin-2-yl amino propane-1,3-diol, compound 128 pmid: 26686393, 2-4-amino-5-5-iodo-2-isopropyl-4-methoxyphenoxy pyrimidin-2-ylamino propane-1,3-diol, 2-4-amino-5-5-iodo-2-isopropyl-4-methoxy-phenoxy-pyrimidin-2-ylamino-propane-1,3-diol, 2-4-amino-5-5-iodo-4-methoxy-2-propan-2-ylphenoxy pyrimidin-2-yl amino propane-1,3-diol, 2-4-amino-5-5-iodo-4-methoxy-2-1-methylethyl phenoxy-2,4-pyrimidinyl amino-1,3-propanediol
PubChem CID 24883277
IUPAC Name 2-[[4-amino-5-(5-iodo-4-methoxy-2-propan-2-ylphenoxy)pyrimidin-2-yl]amino]propane-1,3-diol
SMILES CC(C)C1=CC(=C(C=C1OC2=CN=C(N=C2N)NC(CO)CO)I)OC

Specifications

Quantity 10 mg
Formula Weight 474.29
Percent Purity >98%
Chemical Name or Material Ro 51
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