Invitrogen™ RNF7 Recombinant Rabbit Monoclonal Antibody (24GB5200)

Rabbit Recombinant Monoclonal Antibody

Brand:  Invitrogen™ MA557230

Product Code. 30276292

Description

RNF7 Recombinant Monoclonal Antibody for Western Blot, ICC/IF, Flow

The protein encoded by this gene is a highly conserved ring finger protein. It is an essential subunit of SKP1-cullin/CDC53-F box protein ubiquitin ligases, which are a part of the protein degradation machinery important for cell cycle progression and signal transduction. This protein interacts with, and is a substrate of, casein kinase II (CSNK2A1/CKII). The phosphorylation of this protein by CSNK2A1 has been shown to promote the degradation of IkappaBalpha (CHUK/IKK-alpha/IKBKA) and p27Kip1(CDKN1B). Alternatively spliced transcript variants encoding distinct isoforms have been reported.

Specifications

• Antigen: RNF7
• Classification: Recombinant Monoclonal
• Concentration: 1.5 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q9UBF6, Q9WTZ1
• Gene Symbols: RNF7
• Immunogen: A synthesized peptide derived from human RNF7 (aa 80-113).
• Quantity: 20 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

• Applications: Flow Cytometry, Western Blot, Immunocytochemistry
• Clone: 24GB5200
• Conjugate: Unconjugated
• Gene: RNF7
• Gene Alias: CKBBP1; CKII beta-binding protein 1; OTTHUMP00000180645; rbx2; Regulator of cullins 2; ring finger protein 7; RING-box protein 2; RNF7; ROC2; SAG; Sensitive to apoptosis gene protein; sensitive to apoptosis, zinc RING finger protein SAG, regulator of cullins 2; zinc RING finger protein SAG
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 19823, 300948, 9616
• Content And Storage: -20°C
• Form: Liquid