Invitrogen™ RNF34 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA567332

Product Code. 15969994

Description

Immunogen sequence: NIVCKACGLSF SVFRKKHVCC DCKKDFCSVC SVLQENLRRC STCHLLQETA FQRPQLMRLK VKDL Highest antigen sequence identity to the following orthologs - mouse 97%, rat 97%.

The protein encoded by this gene contains a RINF finger, a motif known to be involved in protein-protein and protein-DNA interactions. This protein interacts with DNAJA3/hTid-1, which is a DnaJ protein reported to function as a modulator of apoptosis. Overexpression of this gene in Hela cells was shown to confer the resistance to TNF-alpha induced apoptosis, suggesting an anti-apoptotic function of this protein. This protein can be cleaved by caspase-3 during the induction of apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been reported.

Specifications

• Antigen: RNF34
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: RNF34
• Gene Alias: AW061037; AW536122; BC004042; C88279; CARP1; CARP-1; Caspase regulator CARP1; caspases-8 and -10-associated RING finger protein 1; E3 ubiquitin-protein ligase RNF34; FLJ21786; FYVE-RING finger protein MOMO; hRFI; Human RING finger homologous to inhibitor of apoptosis protein; Momo; phafin 1; phafin-1; RFI; RIF; RIFF; ring finger protein 34; ring finger protein 34, E3 ubiquitin protein ligase; RING finger protein MOMO; RING finger protein RIFF; RING-type E3 ubiquitin transferase RNF34; RNF34
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 80196
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Concentration: 0.2 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q969K3
• Gene Symbols: RNF34
• Immunogen: Recombinant Human RNF34. Recombinant protein control fragment (Product #RP-105587).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG