Invitrogen™ RNF213 Polyclonal Antibody

Goat Polyclonal Antibody

Brand:  Invitrogen™ PA518650

Product Code. 11396623

Description

This antibody is tested in Peptide ELISA: antibody detection limit dilution 4,000.

RNF213 is an E3 ubiquitin-protein ligase involved in angiogenesis. Involved in the non-canonical Wnt signaling pathway in vascular development: acts by mediating ubiquitination and degradation of FLNA and NFATC2 downstream of RSPO3, leading to inhibit the non-canonical Wnt signaling pathway and promoting vessel regression. Also has ATPase activity.

Specifications

• Antigen: RNF213
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: RNF213
• Gene Alias: 6030403J01; ALK lymphoma oligomerization partner on chromosome 17; ALO17; C17orf27; D11Ertd759e; E3 ubiquitin-protein ligase RNF213; KIAA1554; KIAA1618; mKIAA1554; MYMY2; Mysterin; MYSTR; NET57; protein ALO17; RGD1308168; RING finger protein 213; RING-type E3 ubiquitin transferase RNF213; RNF213
• Host Species: Goat
• Purification Method: Ammonium sulfate precipitation
• Regulatory Status: RUO
• Gene ID (Entrez): 57674
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.5 mg/mL
• Formulation: TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q63HN8
• Gene Symbols: RNF213
• Immunogen: Synthetic peptide sequence (KTAAVLKWNRE) corresponding to the C-terminus amino acids of RNF213 (aa 5195-5206).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG