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Invitrogen™ RNF12 Polyclonal Antibody

Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA582644
This item is not returnable.
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Description
Immunogen sequence: RSESTSARPS RSERNSTEAL TEVPPTRGQR RARSRSPDHR RTRARAERSR SPLHPMSEIP RRSHHSISSQ TFEHPLVNET EGSSRTRHHV TLRQQISGPE LLSRGLFAAS GTRNASQGAG SSDTAASGES TGSGQRPPTI VLDL Highest antigen sequence indentity to the following orthologs: Rat - 83%, Mouse - 76%.
RNF12 is a RING-H2 zinc finger protein. It has been shown to be a ubiquitin protein ligase that targets LIM domain binding 1 (LDB1/CLIM), and causes proteasome-dependent degradation of LDB1. This protein and LDB1 are co-repressors of LHX1/LIM-1, a homeodomain transcription factor. Alternatively spliced transcript variants encoding the same protein have been reported.
Specifications
| RNF12 | |
| Polyclonal | |
| Unconjugated | |
| RLIM | |
| AL022832; AW743871; CTD-2530H13.3; DKFZp686N06224; E3 ubiquitin-protein ligase RLIM; E3 ubiquitin-protein ligase RNF12; FLJ25923; FLJ41093; FLJ42887; FLJ45986; Ha1r; Hoxa1 regulated; LIM domain-interacting RING finger protein; MGC15161; NY-REN-43; renal carcinoma antigen NY-REN-43; RING finger LIM domain-binding protein; ring finger protein 12; ring finger protein, LIM domain interacting; ring zinc finger LIM domain binding protein; ring zinc finger protein NY-REN-43antigen; RING-type E3 ubiquitin transferase RLIM; Rlim; R-LIM; Rlim1; RNF12 | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 51132 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Immunohistochemistry (Paraffin), Immunocytochemistry | |
| 0.1 mg/mL | |
| PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 | |
| Q9NVW2 | |
| RLIM | |
| Recombinant protein corresponding to Human RLIM. Recombinant protein control fragment (Product #RP-92141). | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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