Invitrogen™ RISC Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA5113363

Product Code. 17141224

Description

RISC Polyclonal Antibody for Western Blot, IHC (P), ELISA

The RNA-induced silencing complex (RISC) is a key player in the regulation of gene expression through RNA interference (RNAi) mechanisms. It operates by utilizing small RNA molecules-such as microRNAs (miRNAs), small interfering RNAs (siRNAs), and PIWI-interacting RNAs (piRNAs)-which are processed from double-stranded RNA precursors by enzymes like Drosha and Dicer in animals, and DICER-LIKE in plants. RISC is a versatile molecular complex consisting of Argonaute proteins as its core component, which guides the complex to the target RNA by complementary base pairing. Once assembled, RISC can recruit other proteins that mediate gene silencing by degrading or inhibiting the translation of the target RNA. This post-transcriptional regulation system is integral to numerous biological processes, allowing cells to control gene expression finely and respond to endogenous and exogenous signals. The functionality of RISC in gene silencing highlights its significance in the broader context of genetic regulation and has implications in therapies that target gene expression through RNAi.

Specifications

• Antigen: RISC
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SCPEP1
• Gene Alias: 2410018F01Rik; 4833411K15Rik; AI957256; HSCP1; MSTP034; retinoid inducible serine carboxypeptidase; retinoid-inducible serine carboxypeptidase; retinoid-inducible serine caroboxypeptidase; retinoid-inducible serine caroboxypetidase; Risc; SCP1; SCPEP1; Serine carboxypeptidase 1; serine carboxypeptidase 1 precursor protein; serine caroboxypeptidase 1; UNQ265/PRO302
• Host Species: Rabbit
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 59342, 74617
• Content And Storage: -20°C or -80°C if preferred
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4
• Gene Accession No.: Q920A5, Q9HB40
• Gene Symbols: SCPEP1
• Immunogen: Recombinant Human Retinoid-inducible serine carboxypeptidase protein (201-452AA).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG