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Invitrogen™ RIM3 Polyclonal Antibody

Product Code. 12858652
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Quantity:
100 μg
Unit Size:
100µg
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12858652 100 μg 100µg
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Product Code. 12858652 Supplier Invitrogen™ Supplier No. PA520475

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Description

Rabbit Polyclonal Antibody

A suggested positive control is human brain tissue lysate. PA5-20475 can be used with blocking peptide PEP-0595.

Rab3-interacting molecules (RIMs) are synaptic proteins are synaptic proteins necessary for neural transmission and plasticity. While both Rim1 and Rim 2 are thought to be effector proteins for Rab3, binding to Rab3 on synaptic vesicles in a GTP-dependent manner, less is known of Rim3. Expression of Rim3 in PC12 cells induced a significant increase in calcium-triggered exocytosis, with no appreciable change in the baseline release, suggesting that it plays a role in the regulation of exocytosis. Rim3 protein localizes primarily to neuronal dendrites and the postsynaptic densities, as opposed to Rim1 which is found in presynapse locations, indicating that Rim3 may contribute to synapse transmission and plasticity.
TRUSTED_SUSTAINABILITY

Specifications

Antigen RIM3
Applications Immunohistochemistry, Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene RIMS3
Gene Accession No. Q80U57, Q9UJD0
Gene Alias A730060M23Rik; KIAA0237; mKIAA0237; Nim2; NIM3; Rab-3 interacting molecule 3; rab-3-interacting molecule 3; regulating synaptic membrane exocytosis 3; regulating synaptic membrane exocytosis protein 3; RIM 3; RIM3; RIM3 gamma; Rims3; RP4-739H11.2; si:ch211-239d6.1
Gene Symbols RIMS3
Host Species Rabbit
Immunogen A 17 amino acid peptide from near the amino terminus of human Rim3.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 242662, 9783
Target Species Human, Mouse
Content And Storage Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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