Invitrogen™ Rhodopsin Recombinant Rabbit Monoclonal Antibody (Rho 1D4)

Codice prodotto.	Quantity	unitSize
17900881	200 μg	200µg

Codice prodotto. 17900881 Fornitore Invitrogen™ N. del fornitore MA547925

Descrizione

Rabbit Recombinant Monoclonal Antibody

Specificity: The antibody binds to the C-terminus of rhodopsin on the cytoplasmic side of disk membranes. The epitope has the following amino acid sequence: 'TETSQVAPA'. A limitation of the 1D4 tag, however, is that it has to be placed at the C-terminus of a protein. This is because the Rho1D4 monoclonal antibody requires a free carboxylate group for high affinity binding. Amidation of the carboxyl group lowers its immunoreactivity to the Rho1D4 antibody by over 100 fold.

Visual pigments such as rhodopsin and porphyropsin are light-absorbing molecules that mediate vision. Rhodopsin consists of an apoprotein, opsin, covalently linked to 11-cis-retinal. This receptor is coupled to the activation of phospholipase C. Porphyropsin consists of opsin covalently linked to 11-cis 3,4-didehydroretinal.

Specifica

• Antigen: Rhodopsin
• Applications: ELISA, Immunohistochemistry, Immunoprecipitation, Radioimmune Assays (RIA), Western Blot, Immunocytochemistry
• Classification: Recombinant Monoclonal
• Clone: Rho 1D4
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 0.02% ProClin 300
• Gene: RHO
• Gene Accession No.: P02699, P08100, P15409, P35359, P51489
• Gene Alias: CSNBAD1; L opsin; Long Wavelength Sensitive opsin; LWS opsin; MGC138309; MGC138311; Noerg1; OPN 2; Opn2; Ops; opsin 2; opsin 2, rod pigment; opsin-2; Red Opsin; retinal rod opsin pigment rh1.1; Rh; RH1; rh1.1; rho; rho protein; rhodopsin; rhodopsin (opsin 2, rod pigment) (retinitis pigmentosa 4, autosomal dominant); Rhodopsin (retinitis pigmentosa 4, autosomal dominant); rhodopsin-like-1.1 rod opsin; Rod Opsin; RP 4; RP4; seven transmembrane light receptor; unknown opsin-like protein; wu:fi06d11; zfo2; zfrho
• Gene Symbols: RHO
• Host Species: Rabbit
• Immunogen: Bleached bovine rod outer segment (ROS).
• Purification Method: Protein A
• Quantity: 200 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 212541, 24717, 30295, 509933, 6010
• Target Species: Human, Mouse, Rat, Bovine, Amphibian, Zebrafish
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG κ