Invitrogen™ Rho Pan Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA5106862

Product Code. 16683295

Description

Antibody detects endogenous levels of total RHOC.

This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. The protein encoded by this gene is prenylated at its C-terminus, and localizes to the cytoplasm and plasma membrane. It is thought to be important in cell locomotion. Overexpression of this gene is associated with tumor cell proliferation and metastasis. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Specifications

• Antigen: Rho Pan
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: RHOC
• Gene Alias: AA017882; AI324259; AI845056; Aplysia ras-related homolog 12; Aplysia RAS-related homolog 6; aplysia ras-related homolog 9 (RhoC); aplysia ras-related homolog A; aplysia ras-related homolog A1; aplysia ras-related homolog A2; aplysia ras-related homolog B; ARH12; ARH6; ARH9; ARHA; Arha1; Arha2; Arhb; ARHC; ARHF; ARHQ; AV026554; epididymis secretory protein Li 42; h12; h6; H9; HEL-S-42; Ifld1; induced in fatty liver dystrophy 1; MST081; MSTP081; oncogene RHO H12; oncogene RHO H6; oncogene RHO H9; plysia ras-related homolog A2; Ras family member A; ras homolog 9 (RhoC); ras homolog A1; ras homolog A2; ras homolog B; ras homolog family member A; ras homolog family member B; ras homolog family member C; ras homolog family member F (in filopodia); ras homolog family member F, filopodia associated; ras homolog family member Q; ras homolog gene family, member A; ras homolog gene family, member A1; ras homolog gene family, member A2; ras homolog gene family, member AB; ras homolog gene family, member B; ras homolog gene family, member C; ras homolog gene family, member f; ras homolog gene family, member F (in filopodia); ras homolog gene family, member Q; RASL7A; ras-like protein family member 7A; Ras-like protein TC10; RAS-like, family 7, member A; ras-related GTP-binding protein TC10; RAS-related homolog 9; Rho cDNA clone 12; Rho cDNA clone 6; rho cDNA clone 9; rho family; Rho family GTPase; rho family GTPase Rif; Rho in filopodia; RHO12; Rhoa; Rhob; RHOC; rhoC GTPase; RHOF; RHOH12; RHOH6; RHOH9; Rhoq; rho-related GTP-binding protein RhoB; Rho-related GTP-binding protein RhoC; rho-related GTP-binding protein RhoF; Rho-related GTP-binding protein RhoQ; RIF; SIG-61; Silica-induced gene 61 protein; small GTP binding protein RhoA; small GTP binding protein RhoC; small GTPase Tc10; TC10; TC10A; Transforming protein RhoA
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 104215, 117273, 11848, 11852, 11853, 23433, 23912, 295342, 387, 388, 389, 54509, 64373, 690130, 85428
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: P08134, P17081, P61586, P61589, P62745, P62746, P62747, Q62159, Q8BYP3, Q8R527, Q9HBH0, Q9JJL4, Q9QUI0
• Gene Symbols: RHOA, RHOB, RHOC, RHOF, RHOQ
• Immunogen: A synthesized peptide derived from human RHOC(Accession P08134), corresponding to amino acid residues K162-L193.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG