Invitrogen™ RHEB Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA520129

Product Code. 12878362

Description

A suggested positive control is mouse brain tissue lysate. PA5-20129 can be used with blocking peptide PEP-0247.

Rheb encodes a member of the small GTPase superfamily and encodes a lipid-anchored, cell membrane protein with five repeats of the RAS-related GTP-binding region. This protein is vital in regulation of growth and cell cycle progression due to its role in the insulin/TOR/S6K signaling pathway. The protein has GTPase activity and shuttles between a GDP-bound form and a GTP-bound form, and farnesylation of the protein is required for this activity. Three pseudogenes have been mapped, two on chromosome 10 and one on chromosome 22.

Specifications

• Antigen: RHEB
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: RHEB
• Gene Alias: GTP-binding protein Rheb; Ras homolog enriched in brain; Ras homolog enriched in brain 2; RAS-homolog enriched in brain; RHEB; Rheb1; RHEB2
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 19744, 6009
• Content And Storage: Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
• Form: Liquid

• Applications: Immunohistochemistry, Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 0.02% sodium azide
• Gene Accession No.: Q15382, Q921J2
• Gene Symbols: RHEB
• Immunogen: A 15 amino acid peptide from the middle region of human Rheb.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG