Invitrogen™ RHEB Monoclonal Antibody (GT39810)

Mouse Monoclonal Antibody

Brand:  Invitrogen™ MA527777

Product Code. 16362284

Description

Positive Control: SK-N-SH Predicted Reactivity: Mouse (98%), Rat (99%), Zebrafish (90%), Xenopus laevis (91%), Pig (99%), Sheep (99%), Rhesus Monkey (100%), Bovine (98%) Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Rheb encodes a member of the small GTPase superfamily and encodes a lipid-anchored, cell membrane protein with five repeats of the RAS-related GTP-binding region. This protein is vital in regulation of growth and cell cycle progression due to its role in the insulin/TOR/S6K signaling pathway. The protein has GTPase activity and shuttles between a GDP-bound form and a GTP-bound form, and farnesylation of the protein is required for this activity. Three pseudogenes have been mapped, two on chromosome 10 and one on chromosome 22.

Specifications

• Antigen: RHEB
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with no preservative
• Gene Accession No.: Q15382, Q62639, Q921J2
• Gene Symbols: RHEB
• Immunogen: Recombinant protein encompassing a sequence within the center region of human Rheb. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG2b

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Clone: GT39810
• Conjugate: Unconjugated
• Gene: RHEB
• Gene Alias: GTP-binding protein Rheb; Ras homolog enriched in brain; Ras homolog enriched in brain 2; RAS-homolog enriched in brain; RHEB; Rheb1; RHEB2
• Host Species: Mouse
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 19744, 26954, 6009
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid